Heal the world.
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jeffk8900 I had a measure of 11 ng/mL 12/29/10. Started supplementing around 5000 units and had a 39.5 ng/mL on 5/16/11. Bumped up supplementation range between 5000-10000. Need to get standardized supp levels however.
EriGentry Wow! Were you taking the 5k iu every day? And did you notice any changes before/after?
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jpabello My level was at 34.5 ng/ml back on 12/14/2010, while taking 2000IU per day after a 2 week vacation in Argentina (summertime there). I just had another blood test last week and results should come back in about 2 weeks.
EriGentry Will, how's your D doing? I just finished my course of 4-6k IU/day but haven't done a followup test. Is your level up??
wreinhardt Will test again next week
wreinhardt After 8 weeks of daily 2400 IU I reached 39.8 ng/mL from my baseline of 29. It took more than expected so I will now take 4800 IU to see if I can reach 50.
EriGentry Any idea what happens when Vitamin D is too high? (A friend tested at 86 so want to understand the consequences.)
wreinhardt it looks like a good indicator of overdose may by a metallic taste in the mouth. check out http://www.drugs.com/mtm/vitamin-d.html
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herbaldoc Have been taking 5000iu for 6+ months. 4 months in, on Jan 11, 2011 my 25-OH was 43.1ng/ml. Since my testing up to this point was for personal study, I have no baseline. Will post next set of tests soon!
wreinhardt great info, keep tracking and let us know. thanks
EriGentry Tim Ferriss describes his experience with Vitamin D dosing and testing on pp 513-514 of 4HB: Baseline from first blood test: 32 ng/ml. Second test on 8/30/09 (after two months of taking 1,000 IU/day and 20 min sun exposure daily): 35 ng/ml. Third test five weeks later (after increasing intake to 7,200 IU/day): 59 ng/ml
EriGentry The goal is to get to at least 50 ng/ml, the level at which peak athletic performance happens. 50 is hard to achieve -- it takes persistence full-body exposure to summer sun or supplementation. Tim recommends getting testing first, to establish a baseline, then - if your level is below 50 - taking 6,000 - 10,000 IU/day for 4 weeks. This is very close to what my naturopath recommends: 6k IU/day for a month, then 1k IU/day maintenance. She said Californians have surprisingly low levels of D, despite being in a sunny state. The supplementation helped patients have a better sense of well being. For the record, I'm 2 weeks through taking 4k IU/day D3 and had a baseline of 27. I was not keen to take so much but, after hearing positive reports from my doc, I decided to give it a go.
wreinhardt Starting with a baseline of 29, I am taking 2000 for four weeks, getting another test, and most likely 4000 for four more.
wreinhardt Good point, but because D is fat-soluble and due to varying amounts in multivitamins that people may already be taking it might not be ideal to aim for a true washout and maybe just a starting figure. Thoughts?
gbiggers Yeah, not washout, but starting figure.
wreinhardt yes, I haven't taken any supplements for 3 months. Will get a test and then start soon.
gbiggers wreinhardt-- would you consider making the study title a little more specific? Maybe something like this: "Vitamin D Supplementats and VDR Gene"
wreinhardt may want to consider other genes as well, not sure
gbiggers I happen to have just been tested for Vitamin D (which was ordered before this study was posted-- serendipitous timing!). Blood test on 2011-03-07 showed Vitamin D (25 Hydroxy) concentration of 18.0 ng/ml -- below the National Osteoporosis Foundation recommendation of at least 30 ng/ml.
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wreinhardt have you done a kidney function blood test (creatine, BUN, etc)?
derekja yes, that's the basis for the assertion that kidney function is normal. Borderline normal, but normal. EGFR of 61 last test.
gbiggers Cool study. Should people get a baseline blood test before doing the supplement?
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wellthcare When talking of supplements, which brand or are they all the same??? Is timing and dosing important? If D3 supplementation is truly meant to be effective do we need to understand their dosing and regimen along the lines of taking any therapeutic intervention?
wreinhardt good questions. I at least have been treating different brands the same, but I did notice there are new products offering single vitamin d doses combined with magnesium and calcium so I might try that.